Modukuri, R.K., Monsivais, D., Li, F., Palaniappan, M., Bohren, K.M., Tan, Z., Ku, A.F., Wang, Y., Madasu, C., Li, J.Y., Tang, S., Miklóssy, G., Palmer, S.S., Young, D.W., Matzuk, M.M. (2023) Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. Journal of Medicinal Chemistry, 66 (3): 2143-2160

Zhu, Y., Yue. P., Dickinson. C.F., Yang, J.K., Datanagan, K., Zhai, N., Zhang, Y., Miklóssy, G., Lopez-Tapia, F., Tius, M.A., Turkson. J. (2022) Natural product preferentially targets redox and metabolic adaptations and aberrantly active STAT3 to inhibit breast tumor growth in vivo. Cell Death & Disease, 13(12): 1022

Dawadi, S., Simmons, N., Miklóssy, G., Bohren, K.M., Faver, J.C., Ucisik, M.N., Nyshadham, P., Yu, Z., Matzuk, M.M. (2020) Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library. Proceedings of the National Academy of Sciences of the United States of America, 117(29): 16782-16789

Kiyozumi, D., Noda, T., Yamaguchi, R., Tobita, T., Matsumura, T., Shimada, K., Kodani, M., Kohda, T., Fujihara, Y., Ozawa, M., Yu, Z., Miklóssy, G., Bohren, K.M., Horie, M., Okabe, M., Matzuk, M.M., Ikawa, M. (2020) NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Science, 368(6495): 1132-1135

Chen, Y.C., Faver, J.C., Ku, A.F., Miklóssy, G., Riehle, K., Bohren, K.M., Ucisik, M.N., Matzuk, M.M., Yu, Z., Simmons, N. (2020) C-N Coupling of DNA-Conjugated (Hetero)aryl Bromides and Chlorides for DNA-Encoded Chemical Library Synthesis. Bioconjugate Chemistry, 31(3): 770-780

Oaks, Z., Jimah, J., Grossman, C.C., Beckford, M., Kelly, R., Banerjee, S., Niland, B., Miklóssy, G., Kuloglu, Z., Kansu, A., Lee, W., Szonyi, L., Banki, K., Perl, A. (2019) Transaldolase haploinsufficiency in subjects with acetaminophen-induced liver failure. Journal of Inherited Metabolic Disease, 43(3): 496-506

Simmons, N., Li, J.Y., Miklóssy, G., Modukuri, R.K., Bohren, K.M., Yu, Z., Palaniappan, M., Faver, J.C., Riehle, K., Matzuk, M.M. (2019) Palladium-catalyzed hydroxycarbonylation of (hetero)aryl halides for DNA-encoded chemical library synthesis. Bioconjugate Chemistry, 30(8): 2209-2215

Goebel, E.J., Corpina, R.A., Hinck, C.S., Czepnik, M., Castonguay, R., Grenha, R., Boisvert, A., Miklóssy, G., Fullerton, P.T., Matzuk, M.M., Idone, V.J., Economides, A.N., Kumar, R., Hinck, A.P., Thompson, T.B. (2019) Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity. Proceedings of the National Academy of Sciences of the United States of America, 116(31): 15505-15513

Youn, U.J., Sripisut, T., Miklóssy, G., Turkson, J., Laphookhieo, S., Chang, L.C. (2017) Bioactive polyprenylated benzophenone derivatives from the fruits of Garcinia xanthochymus. Bioorganic & Medicinal Chemistry Letters, 27(16): 3760-3765

Hilliard, T., Miklóssy, G., Chock, C., Yue, P., Williams, P., Turkson, J. (2017) 15∝-methoxypuupehenol induces antitumor effects in vitro and in vivo against human glioblastoma and breast cancer models. Molecular Cancer Therapeutics, 16(4): 601-613 – (Co-First Author)

Li, CS., Ren, G., Yang, BJ., Miklóssy, G., Turkson, J., Fei, P., Ding, Y., Walker, LA., Cao, S. (2016) Meroterpenoids with Antiproliferative Activity from a Hawaiian-Plant Associated Fungus Peyronellaea coffeae-arabicae FT238. Organic Letters, 18(10): 2335-2338

Miklóssy, G., Youn, U.J., Yue, P., Zhang, M., Chen, CH., Hilliard, T.S., Paladino, D., Li, Y., Choi, J., Sarkaria, J.N., Kawakami, J.K., Wongwiwatthananujit, S., Chen, Y., Sun, D., Chang, L.C., Turkson, J. (2015) Hirsutinolide series inhibit Stat3 activity, alter GCN1, MAP1B, Hsp105, G6PD, vimentin, TrxR1, and importin α-2 expression, and induce antitumor effects against human glioma. Journal of Medicinal Chemistry, 58(19): 7734-7748

Li, CS., Ding, Y., Yang, BJ., Miklóssy, G., Yin, HQ., Walker, L.A., Turkson, J., Cao, S. (2015) A New Metabolite with a Unique 4-Pyranone-γ-Lactam-1,4-Thiazine Moiety from a Hawaiian-Plant Associated Fungus. Organic Letters, 17(14): 3556-3559

Talaber, G., Miklóssy, G., Oaks, Z., Liu, Y., Tooze, S.A., Chudakov, D.M., Banki, K., Perl, A. (2014) HRES-1/Rab4 promotes the formation of LC3⁺ autophagosomes and the accumulation of mitochondria during autophagy. PlosOne, 9(1): e84392

Youn, U.J., Miklóssy, G., Chai, X., Wongwiwatthananukit, S., Toyama, O., Songsak, T., Turkson, J., Chang, L.C. (2014) Bioactive sesquiterpene lactones and other compounds isolated from Vernonia cinerea. Fitoterapia, 93: 194-200

Miklóssy, G., Hilliard, T.S., Turkson, J. (2013) Therapeutic Modulators of Stat Signaling for Human Diseases. Nature Reviews Drug Discovery, 12(8): 611-629 – (Co-First Author)

Caza, T.N., Fernandez, D.R., Talaber, G., Oaks, Z., Haas, M., Madaio, M.P., Lai, Z.W., Miklóssy, G., Singh, R.R., Chudakov, D.M., Malorni, W., Middleton, F., Banki, K., Perl, A. (2013) HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE. Annals of the Rheumatic Diseases, 73(10), 1888-1897

Lai, Z.W., Hanczko, R., Bonilla, E., Caza T.N., Clair, B., Bartos, A., Miklóssy, G., Jimah, J., Doherty, E., Tily, H., Francis, L., Garcia, R., Dawood, M., Yu, J., Ramos, I., Coman, I., Faraone, S.V., Phillips, P.E., Perl, A. (2012) N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial. Arthritis & Rheumatism, 64(9): 2937-2946

Niland, B., Miklóssy, G., Banki, K., Biddison, W.E., Casciola-Rosen, L., Rosen, A., Martinvalet, D., Lieberman, J., Perl, A. (2010) Cleavage of transaldolase by granzyme B causes the loss of enzymatic activity with retention of antigenicity for multiple sclerosis patients. Journal of Immunology, 184(7): 4025-4032

Eizert, H., Bander, P., Bagossi, P., Sperka,T., Miklóssy, G., Boross, P., Weber, I.T., Tőzsér, J. (2008) Amino acid preferences of retroviral proteases for amino-terminal positions in a type-1 cleavage site. Journal of Virology, 82(20): 10111-10117

Benkő, Sz., Tőzsér, J., Miklóssy, G., Varga A., Kádas, J., Csutak, A., Berta, A., Rajnavölgyi, É. (2008) Constitutive and UV-B modulated transcription of Nod-like receptors and their functional partners in human corneal epithelial cells. Molecular Vision, 14: 1575-1583

Miklóssy, G., Tőzsér, J., Kádas, J., Ishima, R., Louis, J.M., Bagossi, P. (2008) Novel macromolecular inhibitors of HIV-1 protease. Protein Engineering Design and Selection, 21(7): 453-461

Sperka, T., Miklóssy, G., Tie, Y., Bagossi, P., Zahuczky, G., Boross, P., Weber, I.T., Harrison, R.W., Tőzsér, J. (2006) Bovine leukemia virus protease: comparison with human T-lymphotropic virus and human immunodeficiency virus proteases. Journal of General Virology, 88(7): 2052-2063

Fehér, A., Boross, P., Sperka, T., Miklóssy, G., Kádas, J., Bagossi, P., Oroszlan, S., Weber, I.T., Tőzsér, J. (2006) Characterization of the murine leukemia virus protease and its comparison with the HIV-1 protease. Journal of General Virology, 87(5): 1321-1330

Bagossi, P., Sperka, T., Fehér, A., Kádas, J., Zahuczky, G., Miklóssy, G., Boross, P., Tőzsér, J. (2004) Amino acid preferences for a critical substrate binding subside of retroviral proteases in type 1 cleavage sites. Journal of Virology, 79(7): 4213-4218

Kádas, J., Weber, I.T., Bagossi, P., Miklóssy, G., Boross, P., Oroszlan, S., Tőzsér, J. (2004) Narrow substrate specificity and sensitivity toward ligand binding site mutations of human T-cell leukemia virus type-1 protease. Journal of Biological Chemistry, 279(26): 27148-27157

Bagossi, P., Kádas, J., Miklóssy, G., Boross, P., Weber, I.T., Tőzsér, J. (2004) Development of a microtiter plate fluorescent assay for inhibition studies on the HTLV-1 and HIV-1 proteinases. Journal of Virological Methods, 119(2): 87-93

Citations of Gabriella Miklóssy’s articles can be seen on her Google Scholar profile.

Patents

Tőzsér, J., Berta, A., Csutak, A., Miklóssy, G. (2009) Use of Urokinase Type Plasminogen Activator Inhibitors for the Treatment of Corneal Disorders. EP Patent EP2224949 B1

Tőzsér, J., Berta, A., Csutak, A., Miklóssy, G. (2011) Use of Urokinase Type Plasminogen Activator Inhibitors for the Treatment of Corneal Disorders. US Patent Application 20110028397 A1